Preventing late bleeding in infants with vitamin K deficiency

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Late Vitamin K Deficiency Bleeding in Infants Whose Parents Declined Vitamin K Prophylaxis — Tennessee, 2013

Vitamin K deficiency bleeding (VKDB) is a coagulopathy that develops in infants who do not have sufficient vitamin K stores to support production of clotting factors. In adults, vitamin K is absorbed from food and from vitamin K synthesized by gut bacteria. However, placental transfer in humans is limited; cord blood and infant liver reserve levels of vitamin K are substantially below adult lev...

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Oral mixed micellar vitamin K for prevention of late vitamin K deficiency bleeding.

OBJECTIVE To determine whether the use of mixed micellar vitamin K improves the efficacy of the 3 x 2 mg oral vitamin K prophylaxis schedule. DESIGN Nationwide active surveillance for vitamin K deficiency bleeding (VKDB) complemented with two surveys on the use of the mixed micellar preparation in hospitals and by paediatricians. SETTING AND PATIENTS Infants in Germany in 1997-2000. INTER...

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Intracranial haemorrhage due to late onset vitamin K deficiency bleeding in Hanoi province, Vietnam.

BACKGROUND In many developing countries vitamin K prophylaxis is not routinely administered at birth. There are insufficient data to assess the cost effectiveness of its implementation in such countries. OBJECTIVE To estimate the burden of intracranial haemorrhage caused by late onset vitamin K deficiency bleeding in Hanoi, Vietnam. METHODS Cases of intracranial haemorrhage in infants aged ...

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Vitamin K Deficiency Bleeding: A Case Revealed by Intracranial Haemorrhage

Intracranial haemorrhage in early childhood is associated with a wide variety of causes such as trauma, vascular malformations (aneurysm and arteriovenous malformation), haemorrhagic infarction, brain tumours or blood coagulation disorders (congenital or acquired from coagulation factors). Vitamin K deficiency causes blood coagulation disturbances that can lead to intracranial haemorrhage [1]. ...

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[Prophylactic vitamin K for vitamin K deficiency bleeding of the newborn].

BACKGROUND The administration of vitamin K immediately after birth has shown a significant decrease in the incidence of newborn bleeding, but there is not enough evidence to determine the most appropriate method of administration. The objective of this review is to determine the effectiveness of orally administered vitamin K compared to the intramuscular route in the prevention of hemorrhagic d...

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ژورنال

عنوان ژورنال: BMJ

سال: 1998

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.316.7126.230